Diabetes mellitus and pulmonary arterial hypertension

Authors: Bibiána Kafková
Authors‘ workplace: I. kardiologická klinika LF UPJŠ v Košiciach a VÚSCH a. s., Košice
Published in: Forum Diab 2021; 10(2): 103-107


Pulmonary arterial hypertension is a progressive disorder characterized by pathological remodeling of the pulmonary vasculature, abnormally elevated pressure in pulmonary circulation, leading do right ventricular failure and death. Glucose intolerance and insulin resistance are increasingly thought to influence pathogenesis of pulmonary arterial hypertension, development of right ventricular dysfunction and prognosis of the patient. Modification of risk factors for diabetes and targeted treatment of diabetes mellitus if it develops, may delay the progression of pulmonary arterial hypertension and improve patient quality of life.


diabetes mellitus – heart failure – pulmonary arterial hypertension – right ventricle


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