Long-term anticoagulant therapy in patients with diabetes mellitus and atrial fibrillation – possibilities and hazards

Authors: Matej Samoš 1;  Tomáš Bolek 1;  Dana Prídavková 1;  Rid Škorňová 2;  Kristína Grilusová 1;  Ján Staško 2;  Marián Mokáň 1
Authors‘ workplace: I. interná klinika JLF UK a UNM, Martin 1;  Národné centrum trombózy a hemostázy SR, Klinika hematológie a transfuziológie JLF UK a UNM, Martin 2
Published in: Forum Diab 2021; 10(2): 80-86


Atrial fibrillation (AF) is the most frequent supraventricular heart rhythm disorder in patients with diabetes mellitus (DM). DM is connected with higher risk of stroke and systemic embolism in patients with AF. Recently, it is not entirely clear how efficient and safe is long-term anticoagulation in patients with DM and whether DM affects the clinical efficacy of long-term oral anticoagulation in patients with AF. This article reviews data on efficacy and safety of recently available oral anticoagulant therapy in patients with DM and discusses on some of the hazards and unexplained questions which are connected with this therapy.


atrial fibrillation – diabetes mellitus – direct oral anticoagulants


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