#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Proximal diabetic amyotrophy: case reports


Authors: Miriam Cingelová;  Tatiana Kováčiková
Authors‘ workplace: II. neurologická klinika LFUK a UNB, Nemocnica akad. L. Dérera, Bratislava
Published in: Forum Diab 2018; 7(3): 173-176
Category: Case Report

Overview

The case reports describe the incidence of a less frequent type of diabetic neuropathy – proximal diabetic amyotrophy, manifested by subacute arising of pain and the following rather rapid development of atrophy and muscle weakness of primarily the proximal muscles of the lumbar plexus. The clinical diagnosis was mainly based on patients’ clinical pictures. We used further auxiliary electrophysiological and imaging methodologies to eliminate other causes of peripheral nerve disorders. A basic therapeutic arrangement includes good compensation of diabetes mellitus and stabilization of organ complications, accompanied by symptomatic treatment of pain and pathogenetic therapy, in the area where we are expecting some significant progress in future. Long-term intensive rehabilitation also plays an important role in the treatment management.

Key words:

diabetes mellitus, diabetic neuropathy, intravenous immunoglobulins, proximal diabetic amyotrophy


Sources

1.    Ambler Z, Piťha J. Autoimunitní polyneuropatie. In: Neurologie 2003. Triton: Praha 2003: 95–113. ISBN 80–7254–431–4.
2.    Bansal V, Kalita J, Misra UK. Diabetic neuropathy. Postgrad Med J 2006; 82(964: 95–100. Dostupné z DOI: <http://dx.doi.org/10.1136/pgmj.2005.036137>.
3.    Barohn RJ, Sahenk Z, Warmolts JR et al. The Bruns-Garland syndrome (diabetic amyotrophy). Revisited 100 years later. Arch Neurol 1991 Nov; 48(11):1130–1135.
4.    Bastron JA, Thomas JE. Diabetic polyradiculopathy. Mayo Clin Proc 1981; 56(12): 725–732.
5.    Bednařík J, Ambler Z, Růžička E et al. Klinická neurologie část speciální II. Triton: Praha 2010: 929–930. ISBN 9788073873899.
6.    Bhanushali MJ, Muley SA. Diabetic and non-diabetic lumbosacral radiculoplexus neuropathy. Neurol India 2008; 56(4): 420–425. 
7.    Cibulčík F. Symptomatická liečba diabetickej neuropatie. Súč Klin Pr 2009; 1: 21–24.
8.    Chan YC, Lo YL, Chan ES. Immunotherapy for diabetic amyotrophy. Cochrane Database Syst Rev 2012; (6): CD006521. Dostupné z DOI: <http://dx.doi.org/10.1002/14651858.CD006521.pub3>.
9.    Jensen PG, Larson JR. Management of painful diabetic neuropathy. Drugs Aging 2001; 18(10): 737–749. Dostupné z DOI: <http://dx.doi.org/10.2165/00002512–200118100–00003>.
10.    Katz JS, Saperstein DS, Wolfe G et al. Cervicobrachial involvement in diabetic radiculoplexopathy. Muscle Nerve 2001; 24(6):794–798.
11.    Massie R, Mauermann ML, Staff NP et al. Diabetic cervical radiculoplexus neuropathy: a distinct syndrome expanding the spectrum of diabetic radiculoplexus neuropathies. Brain 2012; 135(Pt 10): 3074–3088. Dostupné z DOI: Dostupné z DOI: <http://dx.doi.org/10.1093/brain/aws244>.
12.    O’Neil BJ, Flanders AE, Escandon S et al. Treatable lumbosacral polyradiculitis masquerading as diabetic amyotrophy. J Neurol Sci 1997; 151(2): 223–225.
13.    Pascoe MK, Low PA, Windebank AJ et al. Subacute diabetic proximal neuropathy. Mayo Clin Proc 1997; 72(12): 1123–1132. Dostupné z DOI: <http://dx.doi.org/10.1016/S0025–6196(11)63674–4>.
14.    Pasnoor M, Dimachkie MM, Barohn RJ. Diabetic neuropathy part 2: proximal and assymmetric phenotypes. Neurol Clinics 2013; 31(2): 447–462. Dostupné z DOI: <http://dx.doi.org/10.1016/j.ncl.2013.02.003>.
15.    Pasnoor M, Dimachkie MM, Kluding P et al. Diabetic neuropathy part 1: overview and symmetric phenotypes. Neurol Clin 2013; 31(2): 425–445. Dostupné z DOI: <http://dx.doi.org/10.1016/j.ncl.2013.02.004>.
16.    Said G, Elgrably F, Lacroix C et al. Painful proximal diabetic neuropathy: inflammatory nerve lesions and spontaneous favorable outcome. Ann Neurol 1997; 41(16): 762–770. Dostupné z DOI: <http://dx.doi.org/10.1002/ana.410410612>.
17.    Said G, Goulon-Goeau C, Lacroix C, Moulonguet A. Nerve biopsy findings in different patterns of proximal diabetic neuropathy. Ann Neurol 1994; 35(5): 559–569. Dostupné z DOI: <http://dx.doi.org/10.1002/ana.410350509>.
18.    Subramaniam N, Chandrashekaraiah S, Christopher MJ. Diagnosis and management of diabetic amyotrophy. Endocrinology 2010; 327–329. Dostupné z WWW: <https://www.gmjournal.co.uk/media/21680/june2010p327.pdf>.
19.    Younger DS. Diabetic lumbosacral radiculoplexus neuropathy: a postmortem studied patient and review of the literature. J Neurol 2011; 258(7): 1364–1367. Dostupné z DOI: <http://dx.doi.org/10.1007/s00415–011–5938–8>.

Labels
Diabetology Endocrinology Internal medicine
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#