Consensual therapeutic algorithm for type 2 diabetes mellitus (in accordance with SPC, ADA/EASD indicative limitations and recommendations )

Authors: Emil Martinka 1;  Vladimír Uličiansky 2;  Marián Mokáň 3;  Ivan Tkáč 4;  Peter Galajda 3;  Zbynek Schroner 5*
Authors‘ workplace: Národný endokrinologický a diabetologický ústav n. o. v Ľubochni 1;  Via medica, s. r. o., Košice 2;  I. interná klinika Jesseniovej LF UK a UNM, Martin 3;  IV. interna klinika UN L. Pasteura Košice a LF UPJŠ v Košiciach 4;  SchronerMED, s. r. o., interná a diabetologická ambulancia, Košice 5
Published in: Forum Diab 2016; 5(2): 99-108
Category: Guidelines

*v spolupráci členov výboru Slovenskej diabetologickej spoločnosti


Type 2 diabetes mellitus is a heterogeneous medical condition involving multiple pathophysiological mechanisms. Its successful treatment requires an individualized approach and frequently combined therapy with utilizing its effect on multiple levels. Current possibilities enable the employment of such procedures to an incomparably greater extent than before. The effects of different classes of oral antidiabetic drugs on the reduction of glycemia and HbA 1c is mutually comparable. However differences are observed in the proportions of patients who met the required criteria, regarding the increase in weight, incidence of hypoglycemia as well as the effect on cardio­vascular, renal or oncologic morbidity and mortality, and severity of specific adverse effects, potential risks and contraindications. The presented text provides the reader with the information about the Consensual therapeutic algo­rithm for the treatment of type 2 diabetes mellitus in compliance with SPC, the ADA/EASD amended indicative limit­ations and recommendations, formulated by the Committee of the Slovak Diabetes Society.

Key words:
agonisty GLP-1 receptor agonists – biguanides – gliflozins – gliptins – glitazones – insulin – sulfonylurea


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