Diabetes mellitus and heart failure


Authors: Ján Murín ;  František Mikla ;  Soňa Kiňová
Authors‘ workplace: I. interná klinika LF UK a UNB, Nemocnica Staré Mesto, Bratislava
Published in: Forum Diab 2016; 5(3): 137-141
Category: Topic

Overview

Diabetes mellitus and heart failure are both diseases with an epidemic presence. In 70ties there were about 3.5 % of dia­betics in our country and today it is about 7 %, but we have about 12.5 % of prediabetics. Prevalence of heart failure is nowadays about 1.5–2.0 %, but in elderly people (≥ 65 years) it is about 10 %. We have some risk factors of heart failure I diabetics: severe hypertension, hyperglycemia, dyslipidemia, diabetic cardiomyopathy, renal dysfunction, ischemic heart disease and obesity with metabolic syndrome. We distinguish two types of heart failure, but a typical type in diabetics is a “diastolic dysfunction” with dysfunction of relaxation of left ventricle. Researchers from Netherland discovered that about a quarter of diabetics suffer a symptomatic and another quarter an asymptomatic heart failure. There is some improvement in the treatment of heart failure in diabetics, and a successful drug is empagliflosine. Also in the inhibition of renin-angiotensin–aldosterone system is a new successful drug, ARNI (angiotensin receptor neprilysine inhibitor) with an ambition to replace ACE inhibitors and sartans. There is an improvement of heart failure treatment in diabetics.

Key words:
type 2 diabetes – heart failure – risk factors – ARNI – empagliflosine


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Labels
Diabetology Endocrinology Internal medicine
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