Why is the treatment of diabetes important a how can be achieved?


Authors: Štěpán Svačina
Authors‘ workplace: III. interní klinika 1. LF UK a Všeobecná fakultní nemocnice, Praha, přednosta prof. MUDr. Štěpán Svačina, DrSc., MBA
Published in: Forum Diab 2013; 2(3): 165-168
Category: Review

Overview

Prediabetes and early stage of development of type 2 diabetes bring significant life, especially cardiovascular risk. Moreover, today it is known that in later stages of progressive diabetes influence of life prognosis is difficult. Therefore we strictly treat prediabetes (lifestyle changes to prevent the transition to diabetes, ev. metformin) and early stage of diabetes as well according to the common european and american recommendations with the gradual addition of antidiabetic agents. Recently is known that even better results can be achieved by early administration of insulin or combination of antidiabetic agents. Such aggressive procedures are not recommended in general, but they demonstrate necessity to deal with diabetes as serious disease, to prevent and treat it very carefully from the early beginning.

Key words:
cardiovascular risk – diabetes prevention – early combination treatment of diabetes – early insulin treatment in type 2 diabetes – early treatment of diabetes – prediabetes – prediabetes treatment


Sources

1. Anand SS et al. Glucose levels are associated with cardiovascular disease and death in an international cohort of normal glycaemic and dysglycaemic men and women: the EpiDREAM cohort study. Eur J Prev Cardiol 2012; 19(4): 755–764.

2. Barr E, Zimmet PZ, Welborn TA et al. Risk of cardiovascular and all-cause mortality in individuals with diabetes mellitus, impaired fasting glucose and impaired glucose tolerance: The Australian Diabetes, Obesity and Lifestyle Study (AusDiab). Circulation 2007; 116(2): 151–157.

3. Zhou XH, Qiao Q, Zethelius B et al. Diabetes, prediabetes and cancer mortality. Diabetologia 2010; 53(9): 1867–1876.

4. Boggs DA, Rosenberg L, Cozier YC et al. General and abdominal obesity and risk of death among black women. N Engl J Med 2011; 365: 901–908.

5. Svačina Š. Prevence diabetu a jeho komplikací. Triton: Praha 2008. ISBN 978–80–7387–178–9.

6. Bhupathiraju SN, Pan A, Malik VS et al. Caffeinated and caffeine-free beverages and risk of type 2 diabetes. Am J Clin Nutr. 2013; 97(1): 155–166.

7. Fried M (ed) et al. Metabolická a chirurgická léčba obezity. Mladá Fronta: Praha 2011. ISBN 978-80-204-2424-2.

8. Nathan DM, Davidson MB, deFronzo RA et al. Impaired fasting glucose and impaired glucose tolerance: implications for care. Diabetes Care 2007; 30(3): 753–759.

9. Svačina Š. Obezitologie a teorie metabolického syndromu. Triton: Praha 2013. ISBN 978–80–7387–678–4.

10. Logue J et al. Do men divelop type 2 diabetes in lowe body massindices then women? Diabetologia 2011; 54(12): 3003–3006.

11. Lean ME, Powrie JK, Anderson AS et al. Obesity, weight loss and prognosis in type 2 diabetes. Diabet Med 1990; 7(3): 228–233.

12. Holman RR et al. UKPDS the first 30 years. Wiley Blackwell: Oxford 2008.

13. de Fronzo RA. Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. Diabetes 2009; 58(4): 773–795.

14. Inzucchi SE, Bergenstal R, Buse JB et al. Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach. Position Statement of the American Diabetes Association (ADA) and European Association for the Study of Diabetes (EASD). Diabetes Care 2012; 35(6): 1364–1379.

15. Weng J, Li Y, Xu W et al. Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial. Lancet 2008; 371(9626): 1753–1760.

16. Svačina Š, Jurašková B, Karen I et al. Doporučené postupy v léčbě starších pacientů s diabetes mellitus v ČR. DMEV 2013; 16(2): 82–92.

Labels
Diabetology Endocrinology Internal medicine
Login
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account